Journal of International Surgery and Clinical Medicine

A Giant Invasive Papillary Breast Carcinoma : A Rare Case Report

Joko Wibowo — 2025-03-18

Introduction: Invasive papillary carcinoma represents a rare subtype of breast cancer, constituting about 0.5% of all invasive breast cancers and mainly occurring in postmenopausal women. Because most information comes from limited case reports and small retrospective analyses, awareness of this tumor remains low, posing challenges for clinical management. There are distinct pathological characteristics and biological behaviors seen in invasive papillary carcinoma, according to the research. One reason for its generally good prognosis is because it is seldom involved with lymph nodes and is classified as a luminal subtype. [1, 2].

Case Presentation: We report a rare case of Invasive Papillary Breast Carcinoma in a 48-year-old premenopausal woman who presented with a gradually enlarging, painless retroareolar mass in her right breast, persisting for four months. The patient previously underwent an incisional biopsy at another hospital, and the histopathology results showed invasive papillary breast carcinoma. The patient has undergone a chest CT-scan for diagnostic confirmation and surgical guidance. The patient underwent a right-sided modified radical mastectomy, and histopathological examination of the specimen confirmed the diagnosis of Invasive Papillary Carcinoma. Immunohistochemical analysis further validated this diagnosis.

Conclusion: Although the treatment of Invasive Papillary Breast Carcinoma generally aligns with that of more common breast cancers, its protocol remains unclear due to the condition's rarity. We chose to present this Invasive Papillary Breast Carcinoma case because of the disease's uncommon nature, the severity of the symptoms, and the need for urgent intervention.

The Relationship Between Ovarian Cancer Stage and Histopathology Features in Operated Patients at Dr.Zainoel Abidin General Public Hospital in Banda Aceh, Indonesia

Hasanuddin — 2025-03-10

Introduction: As the fourth leading of cancer death among worldwide for women, cancer of ovary remains a serious public health issue. Late-stage diagnosis is common and significantly reduces the 5-year survival rate—from 92% in early stages to just 17%–28% in advanced cases. Unspecific symptoms of ovarian cancer cause most patients to present at an advance stage. Histopathology plays a role in diagnosis, prognosis, and decision-making for patient management. Recognizing histopathology early on helps direct therapy and improve patient outcomes. To date, however, no researches have been established on the relationship between ovarian cancer stage and histopathology type at Dr. Zainoel Abidin General Hospital Banda Aceh, Indonesia.

Methods: This study utilized a retrospective cross-sectional design, gathering data from medical records from patients with cancer of ovary treated between January and December 2024. Statistical analyses, including univariate and bivariate tests, were conducted using the Kruskal-Wallis method and SPSS version 26.0

Result: Analysis of the relationship between surgical stage and histopathological features revealed a statistically significant correlation, with a p-value of 0.000.

Conclusion: Surgical staging can be considered when developing appropriate therapeutic strategies while awaiting histopathology results. This allows patients to receive treatment as soon as possible.

Evaluation of Postoperative Maturation of Brachiocephalic Arteriovenous Fistula in Chronic Kidney Disease Patients Using Doppler Ultrasonography

Urmila Fiska — 2025-03-15

Introduction: An arteriovenous fistula (AVF) is the preferred method of vascular access for patients with end-stage chronic kidney disease (CKD) undergoing hemodialysis. This study aimed to investigate whether there is a difference in the post-operative maturation of brachiocephalic AVFs at 6 weeks compared to 8 weeks in CKD patients, utilizing Doppler ultrasonography at RSUDZA Hospital.

Methods: The study involved a sample of 16 patients who underwent brachiocephalic arteriovenous fistula (AVF) surgery at Zainoel Abidin General Hospital (RSUDZA) in Banda Aceh, between November 13 and December 14, 2023. This observational study utilized a prospective cohort design, and data analysis was performed using the Wilcoxon test, with a significance level set at p < 0.05.

Results: The study found that most patients who underwent brachiocephalic arteriovenous fistula (AVF) procedures were women, particularly those aged between 56 and 65 years. Doppler ultrasonography was used to evaluate the patients at 6 and 8 weeks after the surgery. The results showed that 40% to 50% of patients had not met the maturation criteria set by KDOQI by the 6th week, and 30% to 40% still had not met these criteria by the 8th week.

Conclusion: There is no significant difference in the post-operative maturation of brachiocephalic AVF for 6 weeks and 8 weeks in CKD patients using Doppler ultrasonography at RSUDZA hospital.